Twin Study, Genetics, And Eppley Cancer Study

Mar 1, 2013

Dr. Gareth Davies, PhD Scientific Director of the Avera Institute for Human Genetics, and Dr. Amy Krie, MD-Oncologist, discuss twin study and a recent cancer study.

The Netherlands Twin Study: DNA has been collected from 4,414 twins in the Netherlands, who have been followed from birth until age 22. The study allowed them to identify new genetic influences on child psychiatric illness which in turn has lead to improved diagnostic and treatment approaches. The project was the first single nucleotide polymorphism (SNP)/copy number variation (CNV) and genome-wide association study of common childhood psychopathologies using an extended twin-sibling family study design.

The Eppley Cancer Study is designed to bring cancer experts together, and gather patient information and tissue samples in order to develop improved prevention and treatment strategies in the fight against breast cancer.

Initiatives of the Breast Cancer Collaborative Registry :

  • Whole genome analysis to assist physicians in making best treatment recommendations for their individual patients
  • An e-Breast Cancer Registry to provide patients with personalized cancer prevention and control information
  • An e-Breast Cancer Conference, in which patient cases are reviewed by a multidisciplinary team that collaborates on best treatment protocols
  • e-Breast Cancer Consultation in which breast cancer specialists review cases submitted by oncologists

Dr. Gareth Davies and Dr. Amy Krie

Dr. Gareth Davies and Dr. Amy Krie