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Dakota Midday: 'Father of Tamoxifen'

Tamoxifin has been credited with saving millions of women’s lives. But the story of how an abandoned contraceptive was turned into an effective treatment cancer is a fascinating tale of a failure transformed into a medical breakthrough.

Although he didn’t invent the drug, breast cancer researcher V. Craig Jordan is called “The Father of Tamoxifin.” The drug was originally created to block estrogen in hopes of preventing pregnancy. Jordan was working on anti-estrogens as part of his PhD program at Leeds University in England when he met Arthur Walpole, the patent holder for the drug that became Tamoxifin.

Dr. Jordan is currently professor of breast medical oncology and professor of molecular and cellular oncology at the University of Texas MD Anderson Cancer Center, Houston. He’s speaking Monday, April 13th at SDSU on “The Tamoxifin Tale and Beyond.” His talk begins at 7 pm in the McCrory Gardens Education and Visitor Center.

Dr. Jordan joined Dakota Midday and discussed how being in the right place at the right time made all the difference in the development of Tamoxifin as a breast cancer treatment.

Karl was born to northeastern South Dakota crouton farmers, but was orphaned as a toddler during the Great Salad War (1966-67). Rescued by a flock of chickadees, he grew up in the woodlands of Sica Hollow. Legends of a bird boy living in the trees attracted the interest of renowned ornithologist and amateur bandoneon repairman Dr. Vogel Gehrke. With a handful of suet, Dr. Gehrke coaxed the timid boy down from the trees. He adopted him, named him Karl and taught him not to molt on the carpet. Dr. Gehrke’s book, The Bird Boy of Sica Hollow, was a best seller and Karl became a minor celebrity and teen idol. He appeared as a guest star on numerous television programs, most notably an awkward role on The Love Boat as the boyfriend of Captain Stubing’s daughter, Vicki. After critics panned his 1980 album, Bird Boy Does Disco, Karl retreated from public life and returned to Sica Hollow. Living in an isolated tree house, Karl achieved a reputation as a mystic. Pilgrims and seekers from around the world came to ask him about the meaning of life and for vinaigrette recipes. Growing tired of answering questions, he climbed down from his tree, shaved his massive white beard and took a job as the host of SDPB Radio’s Dakota Midday where he could ask the questions instead. After three years in that position, he ran out of questions and became host of Jazz Nightly instead. Karl makes his home in Vermillion with his charming wife Kari and three delightful children, Kodey, Kasey and Spatula. His hobbies include reciting the alphabet, combing his hair and doing volunteer work with delinquent songbirds.
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